Simone di giovanni, Artist

London, June 27 Intermittent fasting helps change the activity of gut bacteria and increase their ability to recover from nerve damage, according to a study conducted in mice.Researchers from the Imperial College London observed how fasting led to the gut bacteria increasing production of a metabolite known as 3-Indolepropionic acid (IPA), which is required for regenerating nerve fibres called axons thread-like structures at the ends of nerve cells that send out electro-chemical signals to other cells in the body.This novel mechanism was discovered in mice and is hoped to also hold true for any future human trials. The team states that the bacteria that produces IPA - named Clostridium sporogenesis is found naturally in the guts of humans as well as mice; and IPA is present in human's bloodstreams too."There is currently no treatment for people with nerve damage beyond surgical reconstruction, which is only effective in a small percentage of cases, prompting us to investigate whether changes in lifestyle could aid recovery," said Professor Simone Di Giovanni from Imperial's Department of Brain Sciences."Intermittent fasting has previously been linked by other studies to wound repair and the growth of new neurons - but our study is the first to explain exactly how fasting might help heal nerves,"Di Giovanni added.The study, published in the journal Nature, assessed nerve regeneration of mice where the sciatic nerve the longest nerve running from the spine down the leg was crushed. Half of the mice underwent intermittent fasting (by eating as much as they liked followed by not eating at all on alternate days), while the other half were free to eat with no restrictions at all.These diets continued for a period of 10 days or 30 days before their operation, and the mice's recovery was monitored 24 to 72 hours after the nerve was severed.The length of the regrown axons was measured and was about 50 per cent greater in mice that had been fasting.Importantly, when IPA was administered to the mice orally after a sciatic nerve injury, regeneration and increased recovery was observed between two and three weeks after injury.Disclaimer: This post has been auto-published from an agency feed without any modifications to the text and has not been reviewed by an editor

Home

City

Latest News

Cricket

LT Premium

National

International

Maharashtra

Opinions

Chhatrapati Sambhajinagar

Nagpur

Entertainment

Photos

Business

Technology

Sports

Lifestyle

Social Viral

Lokmat Games

Health

Pahalgam Terror Attack

Tahawwur Rana

IPL 2025

CM Devendra Fadnavis

Mumbai Local

Weather Update

Simone Di GiovanniFOLLOW

Simone di giovanni, Latest News

Health :Researchers find epigenetic treatment can aid regrowth of sensory, motor neurons in spinal cord

Currently, there are no effective treatments for spinal cord injury; physical rehabilitation can help patients regain some mobility, but the outcomes are severely limited in severe cases due to the failure of spinal neurons to regenerate naturally af ...

Health :Intermittent fasting may help heal nerve damage: Study

London, June 27 Intermittent fasting helps change the activity of gut bacteria and increase their ability to recover ... ...