Takamichi nakamoto, Researcher

One of the most basic senses of animal species is the sense of smell. It is essential for finding food, recognising attractiveness, and detecting danger. Humans detect odorants using olfactory receptors found in olfactory nerve cells. These odorant sensory impressions on nerve cells are linked to their molecular and physicochemical properties. This enables scents to be tailored to generate the desired odour impression. Current approaches can only predict olfactory perceptions based on odorant physicochemical properties. However, that approach cannot forecast sensing data, which is required for producing odours.The findings of the study were published in the journal PLoS One.To tackle this issue, scientists from Tokyo Institute of Technology (Tokyo Tech) have employed the innovative strategy of solving the inverse problem. Instead of predicting the smell from molecular data, this method predicts molecular features based on the odor impression. This is achieved using standard mass spectrum data and machine learning (ML) models. "We used a machine-learning-based odor predictive model that we had previously developed to obtain the odor impression. Then we predicted the mass spectrum from odor impression inversely based on the previously developed forward model," explains Professor Takamichi Nakamoto, the leader of the research effort by Tokyo Tech.The mass spectra of odor mixtures is obtained by a linear combination of the mass spectra of single components. This simple method allows for the quick preparation of the predicted spectra of odor mixtures and can also predict the required mixing ratio, an important part of the recipe for new odor preparation. "For example, we show which molecules give the mass spectrum of apple flavor with enhanced 'fruit' and 'sweet' impressions. Our analysis method shows that combinations of either 59 or 60 molecules give the same mass spectrum as the one obtained from the specified odor impression. With this information, and the correct mixing ratio needed for a certain impression, we could theoretically prepare the desired scent," highlights Prof. Nakamoto.This novel method described in this study can provide highly accurate predictions of the physicochemical properties of odor mixtures, as well as the mixing ratios required to prepare them, thereby opening the door to endless tailor-made fragrances.It looks like the future of odor mixtures smells good!( With inputs from ANI )Disclaimer: This post has been auto-published from an agency feed without any modifications to the text and has not been reviewed by an editor

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Takamichi nakamoto, Latest News

Technology :Researchers discover new method to create tailored odors and fragrances with help of machine learning

One of the most basic senses of animal species is the sense of smell. It is essential for finding food, recognising attractiveness, and detecting danger. Humans detect odorants using olfactory receptors found in olfactory nerve cells. These odorant s ...